While involved in television and other video production, I've used a variety of headphones, earbuds, and other high quality sound systems over the years. These are undoubtedly among the very best I've ever used. The audio response is excellent — very wide range, beyond the range of my hearing, with crisp highs and resounding lows.
The active noise canceling works well enough to noticeably improve and boost the sound quality, and (for once) these headphones worked perfectly, the first time, no configuring necessary. I work in a noisy environment, where hearing audio clearly (and filtering out surrounding noise) is imperative. These are a great way for me to achieve that.
The extra loop helps keep them in my ears, and the comfort level of these is just wonderful as well. Because of it's shape (to accommodate the high fidelity speakers, no doubt), I would suspect that they would fit some people better than others, particularly in terms of sealing off the ears from external sounds; However, there are three different soft silicon covers, so I suppose they would work well for nearly everyone.